Scientific and resource library
Explore our curated library of materials to support and extend the EpiFundamentals content. Access latest research insights and download helpful assets to support your understanding of epithelial science. Remember to check back as the library will be updated regularly
Explore our curated library of materials to support and extend the EpiFundamentals content. Access latest research insights and download helpful assets to support your understanding of epithelial science. Remember to check back as the library will be updated regularly
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Explore this interactive pdf, co-created by Professor Ian Pavord and Assistant Professor Simon Couillard, to learn more about various milestones in asthma research and management throughout history to the present day
Watch Professor Ian Pavord and Assistant Professor Simon Couillard discuss various key milestones in asthma research and management throughout history to the present day
Listen to Dr Del Dorscheid and Professor Andrew Menzies-Gow discuss the importance of the epithelium in severe asthma, differences between the epithelial cytokines, and the importance of preventing airway remodelling
Listen to Drs Andréanne Côté, Jonathan Corren, Del Dorscheid and Professor Andrew Menzies-Gow discuss the clinical challenges of using inflammatory biomarkers to assess patients with severe asthma
Learn more about the histological features of airway remodelling in asthma and their associations with epithelial cytokines
Explore this slide content to learn more about the benefits, limitations and clinical correlates of imaging techniques available for the assessment of airway remodelling in asthma
Explore this slide content to learn more about the different testing methods for airway hyperresponsiveness
Infographic summarising the important roles IL-25, IL-33, TSLP and mast cells play in allergic T2 and beyond T2 pathways
The roles of airway inflammation, airway remodelling and structural changes in airway hyperresponsiveness
Slide deck describing the roles of airway inflammation, airway remodelling and structural changes in airway hyperresponsiveness
Need an overview of EpiCentral's key educational content? Download this slide deck to explore highlights of the 'EpiFundamentals' modules and learn more about the central role of the epithelium
Watch Professor Celeste Porsbjerg and Professor Louis-Philippe Boulet discuss the role of epithelial cytokines in immune response and in the two key hallmarks of asthma, airway inflammation and airway hyperresponsiveness; they also explore the role of cytokines on the clinical features of asthma
Slide content from Professor Celeste Porsbjerg and Professor Louis-Philippe Boulet's expert video discussing the role of epithelial cytokines in immune response and in the two key hallmarks of asthma, airway inflammation and airway hyperresponsiveness; they also explore the role of cytokines on the clinical features of asthma
Watch this video to learn more about the inflammatory cascade that drives asthma pathogenesis and explore how epithelial cytokines initiate inflammation through their effects on various immune cells
Watch this video to learn more about the role of epithelial cytokines in asthma and their role in driving disease pathogenesis
Watch this video to learn more about the pathological changes that occur in the airways of people with asthma and how this manifests as clinical symptoms
Watch this video to learn more about how TSLP interacts with mast cells in asthma, contributing to airway hyperresponsiveness
Watch this video to learn more about damage to the airway epithelium in asthma and the central role of epithelial cytokines in driving inflammatory responses
Download this slide deck to access 3D image stills of the asthma mechanisms of disease video and learn more about the central role of the epithelium in disease pathogenesis
Watch this video to explore the key pathological mechanisms that underpin asthma, and the central role of the airway epithelium and epithelial cytokines in driving disease
Watch this video to see Professor Ian Pavord present a patient case study of allergic asthma with allergic triggers, and learn more about how epithelial cytokines are involved in driving this type of asthma
Watch Professor Christopher Brightling discuss the role of epithelial cytokines in the various inflammatory pathways that underpin asthma and its different phenotypes
Explore this slide content to learn more about epithelial cytokines in the context of the clinical features of asthma, including the impact on everyday clinical practice and patient care
Severe asthma disease burden - infographic
Download this one-page summary infographic detailing the substantial clinical and economic burden associated with severe asthma, despite available treatments
The inflammatory cascade - schematic
Download this one-page summary schematic detailing the three key inflammatory pathways that underpin asthma pathogenesis
Download this one-page summary infographic to learn more about the consequences of sub-optimal disease control in severe asthma
Explore this slide content to learn more about the healthcare burden of severe asthma and unmet need that exists for patients
Download this one-page summary infographic to learn more about the central role of the airway epithelium in inflammation and asthma
Download this one-page summary infographic to learn more about the complexity of severe asthma, specifically the concurrent overlapping inflammatory pathways that may present in patients with asthma
Download this one-page summary infographic to explore the sources, targets and effects of the three key epithelial cytokines involved in asthma disease pathogenesis
Explore this slide content to learn more about the central role of the airway epithelium in asthma and how external triggers initiate the inflammatory mechanisms that underpin the disease